Low MOQs & Startup Friendly | USA & European Market Compliance
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We Formulate Safe, Effective
Oral Care Products

With laboratories and offices in Yunfu and Foshan, Guangdong, our team of 10+ chemists and formulation scientists develops toothpaste, mouthwash, and oral spray formulations that meet global quality standards — from concept to compliance-ready batch.

Cinoll scientists researching oral care active ingredients under microscope
Ingredient Research

Matching the Right Ingredients to Your Product Goals

We study a wide range of active and functional ingredients, then combine them based on each client's target claims and consumer needs. Whether you need a remineralising toothpaste with 10% nano-hydroxyapatite, a CPC-based antibacterial mouthwash, or a breath-freshening oral spray with zinc and essential oils — our team builds the formulation around your outcome.

Every ingredient we use is vetted for safety, sourced from qualified suppliers, and traceable to origin. We maintain an in-house ingredient database covering actives, humectants, preservatives, flavour systems, and functional excipients.

Explore Ingredient Library
Remineralising
Nano-Hydroxyapatite
Up to 10% concentration. Enamel repair and sensitivity relief.
Whitening
PAP & Peroxide Systems
PAP, H₂O₂ and carbamide peroxide for safe whitening formulas.
Antibacterial
CPC & Zinc
Cetylpyridinium chloride and zinc-based actives for mouthwash and oral spray.
Natural
Xylitol & Botanicals
Xylitol, aloe vera, green tea extract — natural and sustainable alternatives.
Sensitivity
Potassium Nitrate
KNO₃ at 5% for clinically proven dentinal hypersensitivity relief.
Safety & Testing

Every Formula Tested Before It Reaches Your Customer

Our testing protocol is structured in two stages — sample-stage and bulk-production stage — so issues are caught early, not after tooling or production investment.

Cinoll laboratory team conducting safety and stability testing
ISO 21149
Microbial Testing
ICH Q1A
Stability Testing

Sample Stage Testing

  • –3-day accelerated stability test
  • –pH measurement (toothpaste 6.5–8.0 / mouthwash 4.5–7.0)
  • –Viscosity verification (rotational viscometer)
  • –Colour comparison (spectrophotometer)
  • –Organoleptic evaluation — scent, texture, appearance

Bulk Production Testing

  • –3-month real-time stability test (ICH Q1A)
  • –Microbial testing (ISO 21149 / ISO 11930)
  • –Packaging compatibility testing
  • –COA, SDS & full compliance documentation

Third-Party Lab Testing (via Partner Labs)

  • –Heavy metal testing — ICP-MS (SGS / Intertek)
  • –Fluoride content testing — ISE method
  • –Packaging compatibility (HDPE / PET / aluminium tube)

Compliance Documents Included

  • –Certificate of Analysis (COA)
  • –Safety Data Sheet (SDS)
  • –Stability test reports
  • –CPSR support for EU / UK market registration
Global Compliance

Formulated for Your Market.
Documented for Your Regulator.

We work closely with a cosmetic R&D and regulatory team based in the United Kingdom to develop formulations that comply with both China's NMPA regulations and the EU Cosmetics Regulation (EC No 1223/2009). This dual-track approach means your product is ready for both Eastern and Western markets from day one.

When your brand is ready to register locally, we provide the full technical documentation package your regulatory consultant will need — including formulation disclosure, ingredient safety data, stability reports, and manufacturing site information.

Ask About Compliance Support

China NMPA

Cosmetics registration documentation and formulation compliance for the Chinese market.

EU Cosmetics Reg.

EC No 1223/2009 compliant formulations. CPSR-ready safety assessment documentation.

US FDA

Cosmetic and OTC monograph guidance for fluoride toothpaste (21 CFR Part 355).

UK CPSR

UK-specific cosmetic product safety report support via our UK-based R&D partner team.

Formulation Innovation

Three Ways to Develop Your Oral Care Formula

Whether you need a fully custom formula built from scratch, a fast-track modification of an existing base, or a proven ready-to-go formula — we have a development path that fits your timeline and budget.

Full Custom

100% Custom Formulation

For brands that want a truly proprietary product. We develop your formula from the ground up based on your product specifications, target consumer, and desired functional claims.

1Formula analysis & brief alignment
2Raw material selection & stability screening
3Functional performance evaluation
4Packaging format recommendation & compatibility testing
Fast-Track

Modify an Existing Base Formula

For brands with a tighter launch timeline. Choose one of our proven base formulas and we adjust the active concentration, flavour system, colour, or texture to match your brand.

1Select base formula from our library
2Define adjustment parameters
3Sample production & approval
4Bulk production with full QC
Ready-to-Go

Select from Our Formula Library

For brands that want the fastest possible path to production. Choose from 200+ stable, tested formulas and go straight to packaging and production.

1Browse formula library by category & claim
2Confirm formula & packaging format
3Artwork approval & production scheduling
4Bulk production & shipment
Cinoll formulation team — professional oral care chemists
Why Cinoll Tech Lab

Efficiency and Rigour.
Never One Without the Other.

Our streamlined development process supports fast iteration and flexible production without compromising on compliance or quality.

Fast Iteration

From brief to sample in as little as 7–14 days for standard formulas.

Regulatory Rigour

NMPA, EU, and US FDA compliance built into every formula from the start.

Professional Chemistry Team

Chemists with 20+ years of oral care formulation experience.

Sustainability-Forward

Waterless toothpaste tablets, solid paste formats, and eco-friendly packaging options.

Formula Spotlight

A Stable 10% Nano-Hydroxyapatite Toothpaste, Ready to Scale

Nano-hydroxyapatite (nHA) is one of the most technically demanding oral care actives to formulate at a clinically relevant concentration. After multi-batch R&D and accelerated stability testing, our team has a production-ready 10% nHA toothpaste formula — validated, documented, and available for private label.

Remineralisation — Deposits calcium and phosphate ions onto demineralised enamel, mimicking natural tooth mineral structure.
Sensitivity relief — Physically occludes exposed dentinal tubules without potassium nitrate.
Fluoride-free — Ideal for natural, clean-label, and paediatric positioning in US, EU, and UK markets.
Packaging-ready — Validated in ABL and PBL laminate tubes; standard 75 ml and 100 ml formats.
Request This Formula →
Cinoll R&D team reviewing nano-hydroxyapatite toothpaste formula in laboratory
10%
nHA — Clinically Relevant Dose
3 Mo
Accelerated Stability Validated
30 d
Brief to Sample Delivery
FAQ

Common Questions About Our Formulation Services

Can't find what you're looking for? Our team responds within 24 hours.

Ask a Question
How does your team support custom formulation for oral care brands?
Our R&D experts are oral care specialists with over 20 years of formulation experience. We work with Amazon brands, retail chains, dental clinic brands, and DTC startups — developing formulas that meet both technical and commercial objectives. Every formula we propose is validated for manufacturing feasibility before it goes to sample.
Do you develop fully custom formulas, or only work from existing bases?
Both. We offer three development paths: 100% custom formulation built to your specification, fast-track adjustment of an existing base formula, and ready-to-go selection from our library of 200+ stable formulas. Most clients start with a consultation to determine which path best fits their timeline and budget.
Can you innovate in the sustainability space for oral care products?
Yes. We have developed anhydrous (waterless) toothpaste formulas, stable solid toothpaste tablets, and oral care products using sustainably sourced botanical actives. We also advise on sustainable packaging formats — including recyclable aluminium tubes, glass bottles, and biodegradable cartons.
How long does it take to develop a new oral care formula?
For a fast-track adjustment of an existing base, we typically deliver a sample within 7–14 days. For a fully custom formula with novel actives or unique sensory requirements, the development phase is usually 3–6 weeks. We prioritise quality over speed, but our streamlined process means we rarely need more time than this.
Is there a fee for new formula development?
In most cases, formula development is provided as a complimentary service. Our business model is built around manufacturing — R&D is the value-added service we provide to clients who commit to production with us. For highly complex or research-intensive projects, we will discuss any associated costs transparently before work begins.

Insights on Oral Care Formulation

Innovations Proven by Patents

Trusted By Oral Healthcare Brands